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I've had it with these motherfucking snakes on this motherfucking plane!

Something you might shout out when you're fed up with a frustrating situation.
After dealing with aggravating bureaucrats for hours, Joe suddenly shouted "I've had it with these motherfucking snakes on this motherfucking plane!"

From the movie "Snakes on a Plane"

Mount Motherfucker

Known primarily among Marines undergoing training at the School of Infantry at Camp Pendleton, California as the least desirable place to hump a pack. Tops off at "Recon Ridge". Named as such because when you are going up, your thoughts consist of little more than "motherfucker..."
PFC. Smith: Fuuuck, we're doing what for PT today?
PVT. Johnson: A pack run up Mount Motherfucker.
Mount Motherfucker by usmcvegas January 9, 2010

God damn motherfucking 

Stronger than damn, stronger than god damn, and yes, even more powerful than god damn fucking, god damn motherfucking is for when you really god damn motherfucking mean it.

Carl you motherfucking piece of shit gang banging cock sucker! 

tenpenny’s saying to carl johnson in big smoke’s crack lab when he shoots the generator and you have to escape.
“Carl you motherfucking piece of shit gang banging cock sucker!”

"I've had it with these motherfucking snakes on this motherfucking plane!" 

A phrase one hollers when one is sick and tired of a situation. From the film, "Snakes on a Plane"
After hours of dealing with bureaucrats, John suddenly shouted "I've had it with these motherfucking snakes on this motherfucking plane!"

motherflipping

motherflipping a less offensive alternative to motherfucking used when you dont want to be too vulgar
that motherflipping son of a gun broke into my house last night and stole my fleets than tried to sell them back to me
motherflipping by littlejimmie February 23, 2019