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Gonaherpascyphilaids 

The Culmination of the major STD's one can get in life, all bundled together, and powerful enough to evolve to control the Human Body. Once contracted, a person begins to become more of a Douchebag/Dumbass or Slut/Bitch. There is no cure.
Dude, James caught Gonaherpascyphilaids.
How can you tell
He's starting to wear things from Supreme and Yeezy.
Oh no.

GonoherpesyphilAIDS Pox 

The term that everyone has been using for a dramatically bad STD but no one knows what it means…it’s just very bad.
He is soo sick, I think he has GonoherpesyphilAIDS Pox.