tweaking 

an irritation, usually drug related

Man, I shot up heroin and started tweaking on it.

tweaking by suicidal.fairies July 4, 2017

Tweaking 

To make adjustments to, it serious.

Andrew was tweaking his homework assignment.

Tweaking by Andrew Kuntz February 1, 2018

tweaking 

going crazy and/or stupid

Griffin was tweaking when he wouldn't respond to Ava.

tweaking by iridocyclitisistweaking May 25, 2019

Tweaking 

Doing dumb actions or not thinking/being stupid etc.

Yo bro she was tweaking on that test

Tweaking by Bballvball 3000 January 5, 2022

Tweaking 

The state of tripping major amounts of balls, usually intoxicated persons.

Bro I’m seeing flashing lights, nah dawg you’re just tweaking.

Tweaking by Skermypeen69 January 5, 2022

Tweaking 

A person who is actively smoking or shooting meth or crack

Tha man sitting on the curb is tweaking with his girlfriend

Tweaking by Carlos Camargo August 29, 2022

Tweaking 

Someone who can’t take a fucking shower

Brandon: PLEASE EXPLAIN TO ME RIGHT NOW WHY I CANT TAKE A FUCKING SHOWER

Ashvin: Bro Brandon is fucking tweaking

Tweaking by Grand trap house June 14, 2023