An illness that causes someone to believe that they are a large trout, and therefore engage in large trout-related activities, such as swimming up waterfalls and spawning. Large Trout Syndrome can be contracted via contact with fairly small trout that wish they were larger.
Friend: I like your shirt, Craig.
Craig: GLUG GLUG GLRBBSHHH GLUUUUH
Friend: Uh, oh, Craig, you've caught Large Trout Syndrome!
Craig: GLRSHHHHH GLUG GLRSHH GLUUURG
Craig: GLUG GLUG GLRBBSHHH GLUUUUH
Friend: Uh, oh, Craig, you've caught Large Trout Syndrome!
Craig: GLRSHHHHH GLUG GLRSHH GLUUURG
by Admiral Foxface December 2, 2019

A term used in the game Overwatch to signify a Sigma using his barrier to protect a charging Reinhardt.
by The OGP October 13, 2020

by Amazing541 August 18, 2015

by suckitbbbb June 6, 2021

Next to embarrassingly encasing his hairy, little hobbit feet in a variety of fabulously effeminate, insoles-containing stacked-heeled boots, platform shoes and high heels, all the while being a pint-sized petite pathological liar who constantly regurgitates a small man syndrome-induced stream of Todd Howard's tall tales, the terminally insecure and aggravatingly ant-like turbo-manlet Tiny Todd "Tiddly Termite" Howard girlishly enjoys dolling himself up by intermittently donning either a black or brown boys large leather jacket when out on the town and looking for a potential manmore sugar daddy. This is without a doubt just another one of Todd "Heckled Homunculus" Howard's manlet cope and manlet rage-induced, hilariously doomed attempts at emphasizing his obviously non-existent masculinity, which is immediately rendered futile when the inherently effeminate Little Napoleon is absolutely dwarfed by every single grown-up that Tiny Todd "High Five" Howard comes into contact with, like the subhumanly stunted, diminutively delicate, devastatingly dwarfed, petulantly puny and preposterously petite, scandalously stunted little runt of a sissy fairy manlet princess that the whole world most definitely knows him to be.
Melissa: Hey, why is there a brown dishrag lying in the street over there? Ellen: It's one of Todd Howard's boys large leather jackets. The utterly insignificant and microscopically minuscule midget monstrosity was crossing the road when a bee humming bird suddenly swooped down and just carried him away! Melissa: Manlets BTFO.
by ManletDepreciator October 11, 2024

1. An organelle within a plant sell known for containing more nutrients than a smaller vacuole
2. A teacher that leaves class for mysterious reasons
2. A teacher that leaves class for mysterious reasons
Person 1: Large Vacuole just left the classroom again
Person 2: What do you think he's doing?
Person 1: Don't question the Large Vacuole
Person 2: What do you think he's doing?
Person 1: Don't question the Large Vacuole
by SpaggettiRemin67 September 22, 2025

by A large mobi wiener with tape December 25, 2020
