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Wife's Best Friend 

Male Genitalia - The Cock, the Dick, the Penis! etcetera etcetera
From "The Penis Song" - in Monty Python's movie - The Meaning of Life! -
"Isn't it awfully nice to have a penis?
Isn't it frightfully good to have a dong?
It's swell to have a stiffy,
It's divine to own a dick.
From the tiniest little tadger
To the world's biggest prick!
So three cheers for your willy or John Thomas.
Hooray for your one-eyed trousers snake.
Your piece of pork, YOUR WIFE'S BEST FRIEND
Your Percy or your cock.
You can wrap it up in ribbons,
You can slip it in your sock.
Just don't take it out in public,
Or they will put you in the dock
...And you won't - come - back ! "
Wife's Best Friend by Volcanoe Joe January 21, 2009
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Man’s Best Friend

Man’s best friend is the vagina.

Without man’s biological attraction to women and their vaginas, humans would not exist.

A woman's vagina is man’s best friend because it makes him feel amazing and loved during sexual intercourse. Men have been known to go to great lengths to gain access to and protect women's vaginas.
Without Man’s best friend (vaginas) reproduction would be impossible. After Alexa showed me her vagina I couldn't stop thinking about it for a month. It drove me crazy. I almost failed my high school classes.

shake hands with the wife's best friend 

I'm gonna go to the restroom and shake hand's with the wife's best friend.

Man's Best friend 

I have a pointer mix named Abby, SWEETEST DOG IN THE WORLD! She cuddles me if I cry, when I'm mad she comes to me to calm me down, she even does this cute thing where she rests her chin on my leg when she begs for food! She TRULY IS my best friend! Man's Best friend!

Man's best friend 

Man's best friend by Southern Threat November 30, 2020

fisherman's best friend 

Fisherman's Best Friend is a sexual act when a person has a couple of Fisherman's Friend lozenges and then performs cunnilingus. Simply cunnilingus with Fisherman's Friend. The person performing the act could be referred to as fisherman's best friend.
He had a Fisherman's friend and proceeded to eat her out. It was nice and minty and she considered him as her 'fisherman's best friend'.
fisherman's best friend by anon8634 September 14, 2013

National Spoil Your Boy Bestfriend Day 

Spoil your bestfriend, this particular day, your boy bestfriend!
“Why are you so ok with buying me a PS5??”

“Because its national spoil your boy bestfriend day!”