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Son of a biscuit

A slight more polite way to say "Son of a *****"
You stupid son of a biscuit, just shut the front door you mother father
Son of a biscuit by Chris Redmond January 11, 2004

Son Of A Bieber 

Justin: You sound like a twelve year old!
You: Shut the fuck up, son of a Bieber!
Justin: *runs away*
Son Of A Bieber by Feierfox November 18, 2010

son of a fuck you 

Uttered in only the most painful of situations. Most likely stated while the brain is trying to grasp what the fuck just happened to you.
Random Bystander:(gets hit in the face with a baseball traveling 200 miles per hour) THWAK! OUCH! SON OF A FUCK YOU! What the fuck just happened to me? Was I hit by a baseball or just received a roundhouse kick from Chuck Norris?!

Son of a Mother Fucking Shit Cunt Bitch 

Something you say when your very angry or upset.
person 1: Son of a mother fucking shit cunt bitch!

person 2: What?

person 1: Were out of popsicles.

son of a bitch 

1) Worst thing to call your father and 2) a curse used by Dean Winchester to express his great disbelief or anger at a situation.
1) Son: "Dad, how could you?! You son of a bitch!"
Dad: "Don't talk about your grandmother that way!"

2)*watches blonde cheerleader walk into house of murder vic*
Dean: "Son of a bitch."
Sam: "What?"
Dean: "Nothing, call you right back."
son of a bitch by BNILTIAC June 16, 2011

son of a gun 

Back in the early 1800s, the British did something called impressment. During the Napoleonic wars, the British considered any ship that traded with the French an enemy. They would steal the supplies and capture the crew. They impressed the crew into the navy for life. These guys would work as sailors for the rest of their lives and never step on dry land again. If they had a wife, the British would bring the wife aboard the ship. If the wife was pregnant, they would place her on the gun deck near the cannons. When she started having contractions, they would fire the cannons to make her push to have the baby. When the baby was born, it was called a son of a gun. This termis is very negative.
Where's your dad, you son of a gun
son of a gun by Jimfromalabama October 7, 2005