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What in the Mother Fuck? 

“What in the Mother Fuck” you ONLY use in a country accent.
What in the Mother Fuck? You don’t do anything right!

Unholy Mother of Fuck 

An expression used to vent frustration/pain/almost any other feeling expressed by the word fuck, typically as an alternative to mother fucker with the added emphasis of the mother being unholy (except for it is a mother of fuck, and not a fucker of mothers).
Unholy mother of fuck! What is that?!

*stubs toes on coffee table*
UNHOLY MOTHER OF FUCK! FUCKING COFFEE TABLES!

Mother Bitch Fuck

I walked up behind Robert and startled him and he said “Mother Bitch Fuck!”

Mother of Fuck 

Expletive. An expression of awe and appreciation. From the blending of "Mother of God" and "mother fuck."
"Mother of Fuck, what a sweet ass."
"Mother of Fuck, you were hot last night."
Mother of Fuck by Khizzar May 19, 2008

Sweet Mary Mother of Fuck 

An offensive phrase to use when one is under stress. It is synonymous with "Jesus Christ."
Sweet Mary mother of fuck, I didn't do my theology homework

Mother of Fuck. 

The moment you're hit with the supernova of a personalized special kind of "fuck you" to top your life's cake with.
Mother of Fuck. It's not something you say. It's what happens to you.