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when used in a questioning manner, it means "oh yeah?", "is that right?", or "so what you're saying is true?"
"Damn, I just found out that my girlfriend is pregnant."

"Oh shit, word up son?"
word up by m-t-a July 1, 2006
It mean ''what's up?'' or ''what's the word on the street?''. Basically ''What's been happening?'' Usually a greeting.
''Hey Steve Word Up.''
''Nuthin just been chillin'...''
word up by Nathan Ganley June 26, 2003
Agreeing with someone when you are under the influence of drugs, alcohol, pills, caffeine, Glade, etc.
mary: god i wish i had a dick to suck right now
jamie: haha.... word up....
word up by Chi Chi Gonzalez August 21, 2003
A slurred pronunciation of "what up" mainly used by big-city blacks and suburbian whiteboys..
word up, gangsta..?
word up by kaotik_jay May 22, 2004
Word used as a statement or greeting by us gangsters.... Bilbee and Hollypops.
Yo bill
Word
Howsit wording?
Its pretty word
Word up nig!
Word up by Holly and Bilbee April 20, 2006
Used in conjunction with ow in place of saying hello.
Man 1:Word up!
Man 2:OWWWWWWWWWWWWWW!
word up by tommyh January 1, 2005