UPI

Universal Prostate Institute.

A made-up institution to serve as an excuse when somebody asks where you graduated.

George: Do you have a degree in computer science?

Johnson: Oh yeah, I graduated at UPI...

by Bin_NoGoutHavinAss_Chang January 12, 2022

UPI

Unidentified party injury

dude...where'd you get that huge bruise. I don't recall. It's a upi from Saturday night.

by rawr kitty December 30, 2016

UPI

Universal Place Identifier

The UPI for Queretaro is queretaro

by blabloz September 19, 2019

Upie

A word for littles in ddlb/ddlg/mdlg/mdlb to be picked up

"Upie!"

by An non no mass (Anonymous) May 5, 2019

Upis

To shoot a gun at a minor that doesn't know spanish and has two feet with 6 six toes

Oh look an Upis I need to shoot it

by Upis February 4, 2023