A very close and dear friend. Someone who is, or whom you consider, to be a sister. Someone who will never let you down and be by your side for life.
by diorznotwar July 9, 2007

Sissi is the softest girl she likes soft pastel colours, chunky chunky boots and BEANIES! She’s best girl— worldwide cutie gal ❤️
She’s also always secretly planning an assassination.
She’s also always secretly planning an assassination.
by rachelgreen October 16, 2020

bob: "hi sissys!"
barbara: "so what are we doing today, sissys?"
jolene: "me and my sissy are so close! Wow! Just sibling things, haha!"
barbara: "so what are we doing today, sissys?"
jolene: "me and my sissy are so close! Wow! Just sibling things, haha!"
by sissylover3000 August 3, 2019

a little weak wimpy guy who loves to create drama to make up for sad weak miserable existence. No lifer. A perso whos weak.
by drfdr January 16, 2008

Originally defined as "wimp", "pussy" or "weak" the word sissy has morphed into the perfect def'n of a Brazilian footballer.
Brazilian guy: "Hey man, that Brazzer baller is down crying for mom. He's hurt bad!"
Normal guy: "Nah dude, he's just a sissy. Get out the spray. His vagina is sore. Stop complaining and be a man (bitch slaps Brazzer)"
Normal guy: "Nah dude, he's just a sissy. Get out the spray. His vagina is sore. Stop complaining and be a man (bitch slaps Brazzer)"
by BrazzerMike May 13, 2013

There was to bathroom in sight so she went on the other side of the tree, squatted and took a sissy.
by c-hum June 18, 2006

by wicked December 4, 2003
