Not sure how this has no definition yet and generally isn't a more common used figure of speech, because it works in multiple ways.
So, basically
1: If you don't spill anything on the floor, you're not going to have to clean it up
"Can I trust you to work alone for a bit?"
"Yeah bruh, no issues, no tissues"
2: If there's no problems, then you don't need anything to wipe the tears out of your face
"I'm fine"
"You been crying, no issues no tissues sis"
3:
A way to respond to someone inquiring requests from you that you currently don't have any
"Dude, should I get you anything from da store?"
"No issues, no tissues homeboy"
4:
When someone expects one of your experiences to have been way more intense than they really were
"Fell down de stairs"
"Ahh shit musta sucked homie"
"Nah brotha, no issues, tissues"
So, basically
1: If you don't spill anything on the floor, you're not going to have to clean it up
"Can I trust you to work alone for a bit?"
"Yeah bruh, no issues, no tissues"
2: If there's no problems, then you don't need anything to wipe the tears out of your face
"I'm fine"
"You been crying, no issues no tissues sis"
3:
A way to respond to someone inquiring requests from you that you currently don't have any
"Dude, should I get you anything from da store?"
"No issues, no tissues homeboy"
4:
When someone expects one of your experiences to have been way more intense than they really were
"Fell down de stairs"
"Ahh shit musta sucked homie"
"Nah brotha, no issues, tissues"
by Petra Jansen November 10, 2019

Used by males to define a situation of "girl troubles". The afore stated situation commonly involving a bitch.
by Roan Schrift June 16, 2011

by kobracharmer April 19, 2018

by Yomommasbihh January 8, 2022

A non-confrontational device to make your final contribution to a strand of argument. The counterpart of "raising an issue".
"After having raised the point of budget revisions, Jim wanted to get on with other business so he relaxed the issue by alluding to maintaining the integrity of the project cycle."
"Well, it seems we are not going to see eye-to-eye on this so I want to relax the issue by saying just look at article number five."
"Well, it seems we are not going to see eye-to-eye on this so I want to relax the issue by saying just look at article number five."
by Vatu November 28, 2019

by CummanderDuck June 14, 2022

Don't try talkin to Daniel today, cuz he's "issue wise".
Q:Whats Brenda's Problem today?
A: -- she's "issue wise".
Q:Whats Brenda's Problem today?
A: -- she's "issue wise".
by BayBayBay March 27, 2009
