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Spike. A character on the (absolutely amazing) TV show Buffy the Vampire Slayer (1997 - 2003), and later on season five of Angel, the Buffy spring-off. A vampire with a soul that still has a sense of humor (hee, hee, Angel). He got his soul by completing tasks to make Buffy love him as much as she loves Angel.
Spike is Angel's best friend, seeing as they both have souls, even though they try to deny it constantly.
Spike by rosemagnoliaxx April 17, 2010
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Spike Venom 

one of the minor scene queens in the making.she's very different, she doesnt resemble the other scene queens. she's a hairstylist and free-handed photographer. look her up on myspace.
Have you seen Spike Venom?
her pics are the sexx
Spike Venom by XxXSar-uhhXxX January 12, 2009

spike lee joint 

When you’re really expecting one kind of high from a joint and you smoke and you are sort of disappointed but not really because you’re still high but a different kind of high---the joint that you smoke a Spike Lee joint. Origin: it doesn’t live up to the hype.
"Dude, I wanted to get knocked off my ass, not this mellow shit...that was a total Spike Lee joint...it's still kind of tight because I'm high, though."
spike lee joint by Seán Gable April 22, 2006
To knock an airborne character downward at an angle such that the character has no chance of making it back to the stage. Used in the Nintendo Classic Super Smash Bros., and its sequel SSB Melee, to define all such moves. Also known as a Meteor Smash; however, certain moves that spike aren't classified as Meteors, such as Fox's Shine Spike, in which he uses his reflector to knock an opponent downward. Very 1337.
Falco has mad spiking skillz. His down+a has arguably the greatest knockback in the game, with no delay.
spike by 1337 haxxorzz April 20, 2004
When someone become really high after smoking spice, the legal substitute for marijuana.
Dude, I'm so spiced right now, I can't even sign my own name.
Spiced by Jolene Jolene Joleeeen December 3, 2010

Spike and Angel 

Angel didn't directly sire Spike, Drusilla did.
The Master -> Darla
Darla -> Angel
Angel -> Drusilla
Drusilla -> Spike
Spike and Angel by the beast 666 November 1, 2004

Spike Hair 

Vaginal Hair that hasnt been shaved (rough)
"Suck on my spike hair, bitch"
Spike Hair by ApplePie911 March 30, 2012