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derpes

a disease you get from derping too much. very hard to get rid of, in some serious cases it's permanent. *cough* Michael! *cough*
Guy 1: "Maynee, I just came back from the doctor and I tested positive for derpes." Guy 2: "That's derpin' derped up."
by eerisedsaysshutupkevin January 13, 2010
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derp

Sound simultaneously expressing supreme dorkiness and excitement of boston terriers.
derp, derp, derp (repeat until satisfied)
by BT Supreme January 21, 2011
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The Derps

A slang term for Down's Syndrome.
What's wrong with that guy?

Oh, him? He has the Derps.
by The Gnargoyle October 26, 2010
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derp

A derp is the guy in the bright clubby striped shirt who waits in line for 2 hours to get into, well, a club. Granted, it’s nighttime, but the derp still wears the euro-trash sunglasses. The derp has far too much pomade in his hair. On top of this, the derp acts like he is a member of high-society, when in fact the derp is actually just high-maintenance white trash.
let's get out of this bar, it's loaded with derps.
by fycfan#1 March 31, 2005
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derp

Degradingly erotic reproductive practices, recommended only for the most masochistic, wanton harlots. Subject usually has difficulty walking for like a day.
Shut yo' mouth and open yo' legs, bitch, yo' in for some srs derp.
by usernameunavailable November 9, 2011
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derp

A state of being. To be extremely messed up, usually from excessive amounts of good marijuana.
WOW that purple was delicious, DERP!!!
by SAMPSON September 10, 2003
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derp

a word that is used as a filler in order to add a comic relief.

Used by the most awesome person in response to something very outlandish or cute

to express excite during an activity

to express "I Love You" when said 3 times consecutively

said by the cutest girl ever
What the derp?

Berka Derp Derp!

DERP DERP DERP!!!

"yesterday was flipping derp!!"
by cloelzbah February 17, 2010
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