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A question about what another has his attention on. What is he thinking about or busy with? "Up" in this usage is referring to a slag from around the 1930s meaning: occupied with or busy with.
When I saw him he was angry so I asked "what's up?". But he would not tell me what he was angry about.
by Scottmana September 29, 2007
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WHAT'S UP! is just a greeting not a question not asking anything just an aknowledgement/ greeting in passing and the only reply in that tone , you have to listen for the tone, is what's! up and keep it moving. Important listen for the tone.
walking down the street and see someone, eyes meet you both have things to do or nothing to do whatever the case you say, what's up! and you keep it moving. don't just say this in any situation you have to use your senses if you don't have any senses don't try it because if you aint feeling it or you convey it in the wrong way it could be misinscrewed in the wrong way that same what's up? could be a challange or a question in which case if you can't reach for your feelings or senses just say hi, that nuetralizes anything other then the greeting.
by "COODIE" DOG April 19, 2010
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A two letter preposition denoting a vector anti parallel to the local gravitational gradient?
What's up?
A two letter preposition denoting a vector anti parallel to the local gravitational gradient?
You're such a fucking geek!
by AnonymousBoschToo November 29, 2018
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Used to mean "she/he/you is/are very attractive and I would very much enjoy making love to you." It is derived from "A Night at the Roxbury"
Steve: What's up? What's up? What's up? What's up? What's up?
Doug: Steve, slow down.
Steve: I can't help it man, it's hottie overload.
Doug: Just pace yourself.
Steve: Ok... What's up?... 2, 3, 4. What's up?... 2, 3, 4...
by Tonberry2000 April 21, 2009
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An interrogative expression used to request a clarification or repetition of something previously said. Used in place of "what?"
Person 1: "You're not paying attention to me."

Person 2: "What's up?"
by Ian May 2, 2004
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comunication between friends
what's up Fred?
by Erica Abreu July 31, 2003
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A fucking annoying question which people answer incorrectly by saying "The sky dumb idiot" or "The ceiling" like that, it is a feeling question.
RandomGuy"What's up?"
RandomGuy2"The sky idiot"
by Karolz February 10, 2017
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