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Of Course. This one confused me a lot as well.
"Dude, what are you going to be doing tonight?"

"Bowling Ofc."

"What does Ofc mean?"

" Of course, ya dingus."
Ofc by YahhhYeet! May 5, 2018
Of Fucking Course.

Many random internet people use it as of course, but the origin of this acronym is Of Fucking Course.
You: So, does it mean ofc = "of course" is wrong?
Me : OFC
ofc by meeboarsox February 11, 2009
Original Female Character. Used in fanfiction when an original character is inserted into an already existing set of characters/fandom. Often shunned due to fear of Mary Sues, hence it is given as a warning.
Pairing: Legolas/OFC
I'm terrified to use my OFC because some might think of her as a Mary Sue.
OFC by silly_walk January 21, 2005
Oh ofc I’ll come to your party.
Ofc by Hahhahah.hi February 15, 2018
Ohio Fried Chicken b**ch
Meh: Hey bro wanna get some OFC?
Fren: What's that?
Meh: Ohio Fried Chicken b**ch
OFC by TheHumanPotato May 20, 2017
Friend 1: Can you bring me some food please?
Friend 2: ofc!!
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