A carpel-tunnel like disability that is caused after driving for a long amount of time with your hands tightly gripping the wheel.
by Merferker October 9, 2011

The girl looked in the mirror one day and saw knuckles the echidna looking back at her from the other side, and couldn't decide whether to laugh or get infuriated, so she looked around for someone to ask if it was them trying to be funny and not the one in the mirror.
by The Original Agahnim July 23, 2021

The Uganda knuckles meme mainly composed of people clicking their tongues and saying do u no da way while being dressed in a weird red outfit
by fking normies reeeee May 14, 2018

Ryan was handing out a serious serving of road knuckle to his cousin on the family road trip to Disney land.
by Constant Hat December 6, 2023

When the overindulgence of drugs/alcohol initiates the human body to want to fall asleep standing up but bent over with their knuckles draging the ground. When caught or surprised they tend to search for things they didn't even drop.
by MegzMaree June 11, 2024

by Burt Macklin, FBI November 12, 2017

by Johnpiraino84 February 8, 2022
