what's up joe? 

actually, the correct spelling is wassup joe, not what's up joe?. The term means how are you not hi, or hello. It did not come from what's up yo. It came from the last 20 years of urban people using the name joe as a term of endearment; the same way you would use, what's up buddy.

wassup joe, I didn't see you on the block today.

what's up joe? by tiqueda u.l. January 21, 2005

what's up joe? 

A slang term originating from the west side of chicago Meaning the same as hello
but adding joe on the end. evolved from the slang term "yo" see: yo

When u see one of ur ppl that owe u sum money in the streets,
u b like: "what's up joe?"

what's up joe? by meech November 15, 2004

that's what's up 

Originated in Philadelphia circa 1998. When discussing events that are of intrest to both parties. The person that didn't know what was going down would say that's what's up.
usally rhetorical.

Frank:Yo! There's a big concert at the spectrum tonite?
Jonny: that's what's up!

that's what's up by HRM SMK April 2, 2008

What's up 

Used to ask an indiviudal how things are going. Can be responded to in urban settings by using the word Chillin or in Jamaica by saying Cool

A- Yo man what's up?

B- Chilllin

What's up by ICO777 August 12, 2009

wigity wigity what's up my radical broskies, what's shaken bacon? 

A certain persons phase. When I mean "certain persons" I mean me so...DON'T EVEN THINK ABOUT USING IT!!!!!

Me( And ONLY ME )wigity wigity what's up my radical broskies, what's shaken bacon?
Other people: Hey???

wigity wigity what's up my radical broskies, what's shaken bacon? by Boss1,000,000,000,000,000,000! February 22, 2018

what up 

What Up is a phrase commonly used by Barney Stinson, usually heard at the end of a comically appropriate sexual comment, often accompanied by a high five. Its style varies from time to time as do most of Barney's catchphrases, being either high-pitched or low-pitched, oddly pronounced or even not verbally said.

Barney: Open bar for the guys, open casket for the ladies, what up!

what up by hakunama tata July 21, 2019

what's up son

A greeting to a homie or friend. Also can be a greeting from father to son.

Dad says,"What's up son"
Cheez Whiz say,"What's up soooooon"

what's up son by payupmoney January 7, 2012