Perpetual smiling eyes disease

A neurophysiological disorder that occurs in certain people (usually a girl, usually named Kalina) who are irrationally happy all the time. As a result, they are never able to stop their eyes from smiling, even with strenuous effort. It is a very unfortunate condition that causes immense career success and likability. Condition is currently incurable and is spread by direct interaction with others. Please beware.

Jim: “Kalina! What happened with your face?”
Kalina: “....Perpetual smiling eyes disease”
Jim: “...oh...”

by A chocolate flavored quark August 20, 2019

zackley's disease

Pungent feet stench, that can drive away normal humans on a range of 15 meters, and allure carcass-eating beasts like vultures and hyeenas.

Firstly acknowledged in Pantera's video "Three - Watch it Go!", by Dimebag Darrel, Phd.

John Doe: "Whatta hell is that stench?"
Jane Doe: "It's your mother. She has zackley's disease. Die."

by Metalmassacro June 20, 2008

Mad Cow Disease

another way to say PMS

Why is PMS called PMS? Because mad cow disease was already taken

by Blair* December 28, 2005

Aaya's Disease

A disease that makes you a emo/vampire kid

Amethia has the Aaya's Disease

by Someone10101010101010 September 21, 2010

Close Persons Disease

Close persons disease; To unite - bring into contact or bring together a human being regarded as an individual, who has an abnormal condition of an organism that impairs function. This causes discomfort, distress, or death to those in contact with the person

Close Persons Disease; Someone who looks hot from the distance, but not up close.

by Maxxi March 27, 2008

Dickinson's Disease

another xbox related disease similar to Tuffy Tantrum, however the anger is often took out on a younger brother, sometimes being thrown down the stairs. The cause of this is often blamed on the controller but is always the user just being generally shit. the controller will sometimes be put down in protest.

A: His Dickinson's Disease is realy aciting up today
B: yea cos he is dump on fifabowl
A: He will get relegated

by JamieSm1th February 23, 2009

foot in mouth disease

Chronic misuse of slang,and grammatical errors when speaking.

Wow ,Jessie's speech sure was a foot in mouth disease disaster!

by Violet Skye's October 15, 2016