Best girl syndrome is when someone feverishly believes that their favourite character in fiction (typically a female in anime, hence the name) is the best character and will be stubborn in saying that theirs is the best and everyone should like it, and that if they don't they simply say that they know them better and say that the other person is in denial, not considering the fact that other people have different opinions.
Guy 1: god I love insert anime waifu here
Guy 2: nah is insert different anime waifu is better.
Guy 1: fair enough, I just like mine better.
Guy 2: you don't seem to get it, they are better.
Guy 1: ...to you maybe, but I still prefer anime waifu1.
Guy 2: you just aren't giving them a chance! Stop being stubborn about it!
Guy 1: and you have Best Girl Syndrome
Guy 2: nah is insert different anime waifu is better.
Guy 1: fair enough, I just like mine better.
Guy 2: you don't seem to get it, they are better.
Guy 1: ...to you maybe, but I still prefer anime waifu1.
Guy 2: you just aren't giving them a chance! Stop being stubborn about it!
Guy 1: and you have Best Girl Syndrome
by Undert23 November 8, 2019

when you feel like only eating breakfast food
it wears off after eating but in some cases it can be long lasting, peranant, or fatal
it wears off after eating but in some cases it can be long lasting, peranant, or fatal
by galix August 23, 2021

by Bignuts 64 September 13, 2022

when the insides of your anus tear out and find themselves someplace else, anywhere other than where they should be.
John: Aw man, I'm having trouble with this anal disruption syndrome...
Mark: Your what?!
John: *tears his fucking anus in half*
Mark: Your what?!
John: *tears his fucking anus in half*
by thetrueboi June 7, 2018

by adriatick July 17, 2020

(Jay-nuss sin-drome) Similar to an ego death from a DMT experience, however, in this case you are just completely retarded.
by Chork Kang January 19, 2021

by RokPilot April 20, 2023
