The direct translation of this slang word is "for sure my nose"
fo-for
shizzle-sure
my-my
nizzle-nose
Thomas: Dang, this shit is crazyyy
Kelly: Fo Shizzle My nizzle
by kellywellykinz June 5, 2009
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While I concur with the Gap Band's origination of this particularity of the phrase...
Its came to be in more modern times via the "skilliage fo'realiage" of Hip-Hop icon E40 whom originaly dictated the root of Fo'Sheezy, which then evolved as it went to south to LA into "Fo'Shizzle"... indeed history is written "via ferus victorus". However it is always evolving to newer heights.
"fo' shizzle my nizzle" is now "Ph'zz'zz'm'z'lel'le"

But of course my dear comrade!
by SPACEKID September 29, 2005
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used to express feelings of concurence meaning sure my nigga.
person1: whaz up nigga?
person 2: nuttin dogg.
person1:u wanna go smoke a jizzle?
person2: fo shizzle my nizzle.
by bob April 16, 2005
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check it playboy its ya main man danbizzle, fo shizzle my nizzle basicly means for sure or in my language fa sho cuz.
You goin to red's later on daniel? Oh fo shizzle my nizzle
by DanBizzle March 20, 2005
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Originally created by DJ Harvey (a.k.a. "Danny J with his Cap Down Low"). However, suspicions exist that his father actually coined the phrase. Both are working class miners from the ghetto of Sutton.
DJ Harvey: Hey dad, how's life treating you in the mines?
Father: Oh it's all good, fo' shizzle my nizzle.
by Nick334 July 25, 2005
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