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Best Friend Fuck You, simply a best friend that is not your friend anymore. Never again and when you try to be their friend they flip out at you.
Yeah we used to be BF's now were BFFU's.
BFFU by Bill DePasquale April 21, 2008
bffuwd <3
bffuwd by chocolatecookiee December 22, 2008
A word that in German means that lady is mega gay
Gupta: you see her she is bffunf
bffunf by MisterGupta November 11, 2021
(there was this girl she was my bffutts).
bffutts by bibi tate February 12, 2023

bffuyfmbfa 

Acronym for: Best Friends Forever Unless You Fuck My Boyfriend Again
Girl1: Like I'm totally sorry about drunk fucking your BF. It's been 6 months . You gonna keep giving me the silent?

Girl2: He's just as much at fault as you were. I missed you. We BFFUYFMBFA.
bffuyfmbfa by Insidivs August 25, 2010