extra chromie 

When you or someone else has an extra chromosome causing them to be retarded

Bro I think Melisa from the Voice has an extra chromie

extra chromie by PPSOFTBrynanna May 16, 2019

extra chromie homies 

People who have extra chromosomes and are best friends. "Chromie" referring to chromosome and "homie"s referring to " people who are good friends and would die for each other".

People who have extra chromosomes and are friends are considered extra chromie homies. Yesterday, John and I went into the extra chromie homie room by accident.

extra chromie homies by B4dg3r January 12, 2017

Homie with an extra chromie 

Person with Down Syndrome, due to the fact the condition is caused by a person being born with 47 chromosomes instead of 46.

That guy with Down Syndrome is my Homie with an extra chromie.

Homie with an extra chromie by Golden Hawk April 13, 2023

homie with an extra chromie 

That one dude who you know has your back when that autism strikes.

Autistic Child #1: I'm gonna shoot up the school
Autistic Child #1: You cool though.
Me: You my homie with an extra chromie man.

homie with an extra chromie by Phiriz January 30, 2018

extra_chr0mie

a masked sweetheart that is everyones friend and makes good edits

Yo did you see extra_chr0mie yeet that thxt

extra_chr0mie by goodboidrift November 18, 2019