diseased up 

1) person having multiple diseases, i.e. aids, herpes, genital warts, etc. etc. all rolled into one
2) person having one or more uncurable diseases
3) what a professional prostitute is in her later years

"Aww man, dude, don't go out with that girl! Dude she's all diseased up! You'll get something Ajax can't wash off!"

diseased up by digawid July 4, 2008

Head up ass disease 

Head Up Ass Disease, in other words, someone has HUAD when his/her perception of a situation is so unusual or extremely inaccurate, most are left speechless.

She really thinks she's the best thing since sliced bread. She has head up ass disease.

Head up ass disease by ReallyGood January 2, 2012

stick up ass disease 

someone being a major bitch constantly so people think they always have a stick up their ass

I think my boos has a case of stick up ass disease

stick up ass disease by bretttttttttttttttttttt July 30, 2006

Updog Disease 

A serious illness often causing death within the first month of infection. It is not a laughing matter and should be treated with absolute caution. Those that have it often experience symptoms such as build-ups of Ligma, constant Sugma release, finding a unique interest in tapes and CD's, and anal inflammation.

"Why is Aidan not in School?"
"I heard he has Updog disease."
"Oh my god, that is terrible and not a joke in any way"

Updog Disease by Dr. Underthere March 9, 2020