PoopPuke&Die Share definition Flag A severe stomach condition where one feels nauseous and has it cummin outta both ends. See blowout.It looks like and sounded like someone cleaned PoopPuke&Die off the windows. PoopPuke&Die by PineappleJuice March 30, 2015 0 0 Get merch Get the PoopPuke&Die mug. Buy Now — $32.95 See more merch