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chromosome chaser 

A person who is attracted to people with Down's syndrome or some other form of mental retardation.
Damn, that Mike loves his girls stupid -- he's probably a chromosome chaser.

Chromonome 

Alex only has one chromonome left as shown by his inability to form coherent sentences
Chromonome by Kiana S December 9, 2019

Chromosomobile 

"Hey Ricky! Look at that faggot in the chromosomobile!"
Chromosomobile by ❤️‍🔥 September 15, 2021

Y Chromosome 

Evolution's greatest mistake.
That Y chromosome over there has been raping and destroying the Earth for thousands of years.

Revoke your y chromosome 

Basically the equivalent of your not a man anymore.

Used when you see a guy doing something petty like crying or showing their emotions.
Dude did you just cry...? Were gonna have to revoke your Y chromosome.

Chromosome

Black guy: who is comin over, man?
White guy: A few of my chromosomes.
Chromosome by Andy Y. August 6, 2007