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Lost in space 

When a guys dick is so small it practically gets lost in your cooch.
Wow, I didn't know Jhon was so small. Last night we finally did it and he got lost in space.
Lost in space by x3 x3 December 18, 2005

In space, no one can hear you scream. 

This factual statement is a metaphor, which implies being alone, in danger, and in a seemingly hopeless situation.

It originally entered pop culture as the tag line on the Movie Poster for James Cameron's Alien (1979).

This statement is an oversimplification of fact. The vacuum of outer space transmits sound poorly; however, to scream, you need air, and thus others on your spaceship would hear you scream were you able.

This expression emphasizes the terrifying truth that we are truly alone when travelling through outer space. No help is nearby. You and your crew have to be self-reliant.

For its time, Alien was exceptionally scary and realistic, thus the expression is burnt in the American psychic with a sizable connotation of fear, hence the words are memorable to this day.
"Whatever you do, don't get stranded in outer space. Remember, in space, no one can hear you scream."

asses in space 

(N.) When you our your friends do something stupid to make someone laugh.
asses in space by Alex Seidel December 6, 2003

asses in space 

(N.) The best clan for the game Counter-Strike. A.I.S.
Hey, all the Asses In Space are gunna be at CBS later so I'm not going don't want to get my ass kicked.
asses in space by Pissed Off Polak December 6, 2003

mars.in.space_ 

a very gay content creator they love to make edits and has very bad thoughts
Mars.in.space_ is gay

We're on a rock in space

The perfect excuse to literally anything
Meant to symbolize "Nothing really matters"
Also makes you sound super fucking stupid
"Dude, are you sure you wanna eat all those ghost peppers?"

"We're on a rock in space."