Pufferfish hands 

Easy way of saying raynauds syndrome

Mum! My pufferfish hands are acting up! Give me the gloves

Pufferfish hands by Pufferfish hand expert February 19, 2021

Pufferfish spot 

The male G-spot, but with cancerous tumors in its vicinity due to colon cancer.

"Dude, did you hear that Fred was diagnosed with colon cancer?"
"Yeah, a shame. I hope it's not terminal."
"Heh, only thing I'm worried about is how good that Pufferfish spot feels."
"You sick fuck."

Pufferfish spot by EvoDump September 23, 2021

Pufferfish bellend 

Where a man has a prickly bellend from pounding his mums pillow.

James has a pufferfish bellend from his experience with his mums pillow

Pufferfish bellend by Bigmanbigshlong January 14, 2019

Pufferfish Ass 

Pufferfish Ass is used in a sentence that means literally just Pufferfish Ass alone. It's a lame inside joke that only a few people would get if their sense of humor is clearly broken.

Person 1: Hey, Pufferfish Ass
Person 2: LOL shut up

Pufferfish Ass by thotfulass November 7, 2020

PUFFERFISH_24 

Some pufferfish who somehow rose to become the Premier of the Soviet Union.

“Yo, PUFFERFISH_24 said that PTS equates PT”
“PT moment”

PUFFERFISH_24 by PofferIturbide March 5, 2021

Pufferfish Care 

A furry

Person 1 "Pufferfish Care is my favorite YouTuber"
Person 2 "Pufferfish care is a furry"

Pufferfish Care by TwinklyToedTyler June 14, 2023

Pufferfish Ego 

(noun) An inflated sense of self-importance that balloons dramatically in response to even the tiniest wins or crumbs of praise.

Mr asshat: "lol i killed you once which means i'm better"
John: "After losing 500 times, holy Pufferfish Ego

Pufferfish Ego by Nirvloyd February 11, 2025