Skip to main content
an iso (short for isolation) is a 1 on 1 situation at a party between a girl and guy in which one person in the conversation is trying to rizz the other. The topic of an iso typically emerges when a guy and a girl are initially in a larger group, but either the guy or girl wants to make a move on the person of the opposite gender. A person can "request" an iso from the other members of the larger group (in which the other members would leave the couple alone), or the members of the larger group can "give" the couple an iso and leave them alone to let the couple cook.
Ex 1: "Hey Katie, can you give me the iso with Jill? I need to rizz this chick and take her home with me."

"Of course, Brad. I will leave immediately"

Ex 2: "Hey Spencer, I see you spitting mad game to Madeline Woods. I'll give you this iso."

*Spencer fist bumps Parker and Parker walks away*
Iso by TheRizzler69 May 26, 2024
Related Words
Isobel ISO isopod Isolde isolation isosceles ISOB iSOK Ísold isobella
Iso is short for isolation. It’s when one player goes 1-on-1 against a defender, and the rest of the team moves out of the way.
Kyrie gets the switch on curry and calls an ISO at the top of key, he cooks his defender and scores a side-step three.
Iso by ki40 June 21, 2025
ISO means isolation play. It’s when one player goes 1-on-1 against a defender, and the rest of the team moves out of the way.
Kyrie Irving got the ball and called for an ISO , meaning he wanted to take his defender 1-on-1. That defender was Stephen Curry.
Iso by ki40 June 21, 2025
the richest & biggest
ladygloks: omg hes iso?

18felonn: girl yesss
ladygloks: i just KNOW he got a bag
iso by reallypaid July 7, 2025
“iso” is a genre created by xenbrixx packed with tons of melodic elements such as low and high strings, relaxing pads, delayed bells, and delayed percussion. But the ear scratching leads, chopped voxes, paused crashes, and hard hitting drums is what brings it all together. The sound was created in mid 2024 and originally “iso” was an alternate version of dulcettrap, But eventually became something else entirely.
i had and idea that lead to more ideas if that makes sense. iso beats are so good because of how simple yet bouncy they are, iso is mellow but can also be upbeat and groovy if needed. no matter what anyone says, all of this came from me and my ideas. - xenbrixx
iso by InSyncRadio August 1, 2025
ISO Gang is the Brooklyn Nets big 3 consisting of Kylie Irving, Kevin Durant and James Harden. These players will ultimately win Brooklyn the NBA Finals and all around beating LeBron by simply not passing, and isoing the play because they’re just that good
Person 1: Man Kyrie never passes the ball
Person 2: cause it’s fuck a pass he ISO’s that shit, ISO gang in 5
iso gang by NetsLevel August 21, 2021