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Smoke me up 

Used to ask someone for (or to return) a favor. Deriving from weed culture for when someone lets you smoke their weed with them for free, is now often used to ask for any kind of favor.
Bro, I’m fuckin broke until I get paid next Friday. Could you smoke me up on a couple beers tonight? I’ll for sure get you back next weekend.

Smoke Em Up 

A term used to describe the act of flooding the enemy with as much smoke as you have. The smoke comes from smoke grenades, and this term is used commonly on first person shooters.
Bill- "Yo man, there are 5 guys in that house!"

Jack- "Smoke Em Up and run in there!"
Smoke Em Up by Goofry July 2, 2009

Smoke something up 

To develop a new solution to a problem, usually on an impromptu basis.

The expression "What have you been doing, smoking the crack pipe?" led to "You need to back away from the crack pipe" led to "Don't worry about it, we'll just smoke something up to solve that problem."
"What are we going to do about the brand new project requirement that we just received?"

"Don't worry about it, the rest of the team and I will just smoke something up tonight and have it ready for testing tomorrow."

Smoke You Up 

The sexual interaction of blowing smoke up your partner bootyhole.
Joe: I’m tryna smoke you up this Saturday.
Tiffany:ok
Smoke You Up by Smoke me up March 24, 2021

Up In Smoke 

Where my money goes.
Up in smoke, that's where my money goes, in my lungs, and sometimes up my nose.
Up In Smoke by the st[one]r August 6, 2008

Stoked, stroked and up in smoke 

A euphemism for blue balls or the female equivalent. Stoked about getting it, stroked for a little while, and then it all goes up in smoke and nothing happens.
"Man, last night blew. Stoked, stroked and up in smoke."