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Among many OTHER possible definitions, WITHIN the HIP-HOP context, D's/Deez/Dees can stand for DA, deputy, or otherwise law enforcement in general.
Mobb Deep (Hell on Earth) - Here come the D's.
Biggie (Missing U) - We was fine till the D's crept in.
50-cent (In Da Hood) - Now the D's, they harass me in the 'hood.

There are many other examples, just listen to a few albums.
D's by Gman3154 June 6, 2007
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Abnormally large; humongous; gigantic.
John "Check out that girl's D's ass!"
Ian "Holy crap! That is D's!"
D's by fohren39 November 13, 2011
Related Words
d.s. D-Shiznit D-Squad D&S D- Sexual D-squared D-Stack D/s D-Saw D'Sean
Initialism for "dick suck".

Fellatio.
"I got me a 'D.S.' from that skanky chick from down the street."
To get real real drunk and jump into a canal during the day. To get hopped up on pudding and bud lite and jump into body of water
yo! did you hear about Dave. He was having some bud lights at scotty's and decide to do a D.S
D.S by Sharkton January 26, 2011
D's stand for dubs, not to be confused with daytons... d's stand for any rims 20 inches and up... 20's dubs... makes sense doesnt it? people think d's stand for daytons cause of rich boys throw some d's but they didnt have a single shot of dayton wired rims in the whole video
throw some d's on that bitch, just bought a cadillac
d's by master deuce deuce April 23, 2009
Abbreviation for dead sexy; the hotness level in between very sexy and too sexy.
Daymmm!! That girl Charise is SOO D S!
D S by Djoli Starr June 21, 2006
Dinner then Sex
Damn dude i jus had the best D & S at michaels moms house.
D & S by g-rida653 August 11, 2008