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Larskinsons Disease 

A disease that causes people to lose their ability to clap normally
Brendan Fraiser is the perfect example of someone who has Larskinsons Disease.
Larskinsons Disease by Kif23 February 14, 2012

hanahaki disease 

a fictional (emphasis on fictional) disease, often used in fanfictions, where the victim regurgitates and coughs up flower petals when they suffer from unrequited love. The illness can only be cured through surgical removal, however any existing romantic feelings are also removed with the infection.
the "hanahaki disease" can't really be applied to real life because it's fictional, so no examples for it...sorry!

Edward Cullen Disease 

When one (normally a Twitard or Twihard) becomes extremely obsessed with Edward Cullen from Twilight.
Twitard: OMG I LUV EDWARD!!!111 HES SO HAWT!!11111

Me: Another victim of Edward Cullen Disease passes by...

Hotchner's Disease 

Hotchner's Disease is basically where you only smile like maybe 5 times in 5 yrs. Treatment - Have JJ show you her newborn son.
Guy #1: Dude i need to see JJ's kid again.
Guy #2: You got Hotchner's Disease again?
Hotchner's Disease by Team Reid February 20, 2011

Madison Disease 

When you're eWhoring and you sell your pictures/videos for less than a dollar each or charge less than $20 for a package
you selling a single pic for $5? you got the madison disease bro
Madison Disease by madisondisease August 18, 2021

Crone’s Disease 

When a woman reaches an age where she no longer gives a rat’s ass if others find her appealing.
Clearly this one-time hottie is suffering from an advanced case of Crone’s Disease.
Crone’s Disease by Dr Bunnygirl January 9, 2019