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Joe says No 

A mouse that lives in someones vagina (along with other STDs) that says "No" and closes the vagina if it doesnt want sex. Joe, the mouse usually wants sex because he has low self esteem.
If a man tries to have sex with a girl Joe may say no, but he probably wont.

Joe says no
Joe says No by Bitchz July 9, 2014
As said by DaithiDeNogla when Joe peed on his keyboard.
No Joe you peed on my keyboard!
No Joe by Jazzymations January 15, 2018

No Joe Pa 

A phrase said to deny gayness when partaking in an action that can be deemed homosexual in any way. It is very similar to the meaning "no homo", except refers to allegations against Penn State and longtime former head coach Joe Paterno.
The camp counselor called out No Joe Pa as he strapped the climbing harness on the camper.
No Joe Pa by jwags1568 November 26, 2011

no mouse joe 

no mouse joe is a nickname given to Joe, when Steven ubor jacks Joe's mouse, thus not able to use a mouse
Which causes Joe to be U!30R-H4><0R3)
in most cases Joe gets back his mouse
"What you going to do now, No mouse Joe?"
"Do you have a mouse, no mouse Joe?"
no mouse joe by Duster March 17, 2004

Hell no, Mexican Joe! 

Did you get with that hooker in Tiajuana last night?

Hell no, Mexican Joe!
Hell no, Mexican Joe! by meatgel November 13, 2014

No One Messes with Joe 

Acknowledgement that, no matter what the task, the person appointed will accomplish it.
Person 1-"How is Tim going to stop that nuclear bomb?"

Person 2-"I have no idea, but he will, because no one messes with Joe."