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run up on 

to jump, or momentarily attain a hidden position and then compromise your position with bad intent
so what make's you think imma run up on you with a nine
-50 Cent
run up on by atowneightynizzle November 12, 2003

run up on 

To try to make a move or have sex with somebody
"Whaddup with you and me girl? When we gon' chill?"

"Nigga,Dont even try to run up on my shit!!"
run up on by Bobscout January 9, 2006

Run up on a nigga 

when your about to go up to someone and beat their ass
I'm about to go run up on a nigga and rock his shit
Run up on a nigga by DADDY Ak 🍇 November 28, 2016

run up on your spot

To approach someone with the intention to bring harm. Most commonly with a shank and/or baseball bat wrapped with barbed wire.
"Run up on your spot like CJ from San Andreas!"
run up on your spot by Reg M August 4, 2006

Run Up On The Seat 

This is the maneuver when one has lost all control of the lockage and now has autopilot engaged for the rest of the performance . This can also refer to when one is commended for the stellar activities he/she performs in the space .
Ashton run up on the seat full throttle simultaneously locking the music. " Mdf Adrian dii run on the seat with this outfit bey”
Run Up On The Seat by Town242 June 19, 2021

Devil May Run up on a Nigga 

The only and realest version of Devil May Cry for the PS-Triple as declared by Chad Warden.
Buncha' niggas tryin' talk shit, sayin' that XBOX got dat game "Devil May Cry 4".

Chad Warden dun' give a fuck, aight?

Let dat nigga cry, aight?

Dat nigga be cryin' all the time, let that bitch go to the XBOX 360.
Nigga, let that shit go to the Wii. They used to crying, aight?
If ya'll niggas want a game fo' dat Triple, we got like "Devil May Run up on a Nigga".
Fuck dat shit, aight?