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Pyx is a name for that one girl everyone knows but may not talk to. She associates with the “well known” people, like a Tanvi or a Zacky, but you’ll never get to know her until you message her privately. Once that’s done, you’re sure to have met someone pretty decent.
“Hey, you know that girl Pyx? yeah, she’s kinda mysterious but I talked to her and now we are best friends
Pyx by minoushka July 7, 2018

pyxisdilf 

a really funny tiktoker that goes by the name jennifer. they're really kind, funny, and great company. they deserve the world and more tbh. they also make me bust on a daily basis
Hey, did you see @pyxisdilf's new post?
pyxisdilf by mikasas wife March 28, 2021
A person that has a unique personality, usually calling themselves some sort of goddess.
That Pyxn thought that we should obey her every command.
Pyxn by Meta Kit June 15, 2008
The most funniest, hottest mf on the app.
me: do you follow pyxisgf?
someone weird: no they’re annoying and they’re not funny
me: boy stfu, i’ll literally smack you, i hope you run, trip, and fall then get up and then trip again and then bleed
pyxisgf by yaegerrq March 11, 2021

Pyxisfuzzyballwrinkles 

Zaddy Pyxis came in to your window, dressed in a sailor moon cosplay minus the wig. He bent over you, “can you feel the love tonight?” Was his inspiring words. He finally did the deed of yk yk.. and while doing it he grunted like a Minecraft villager
“Man Pyxisfuzzyballwrinkles really tasted good
from the Greek, for "box". In ancient Greek slang also refers to a woman's vagina.
Man, I'd like to get into that pyxis!
pyxis by tipsybizmark January 20, 2011