A mouse that lives in someones vagina (along with other STDs) that says "No" and closes the vagina if it doesnt want sex. Joe, the mouse usually wants sex because he has low self esteem.
A phrase said to deny gayness when partaking in an action that can be deemed homosexual in any way. It is very similar to the meaning "no homo", except refers to allegations against Penn State and longtime former head coach Joe Paterno.
no mouse joe is a nickname given to Joe, when Steven ubor jacks Joe's mouse, thus not able to use a mouse Which causes Joe to be U!30R-H4><0R3)
in most cases Joe gets back his mouse