Perma-herp 

That sore on your friends face that they never discuss and never goes away.

Did you see Burt Reynolds perma-herp acting up today? I think it's bout to eat his face.

Perma-herp by MasterJRC December 9, 2008

Permaderp 

A state of extended or permanent burnout due to excessive weed smoking.

Distant cousin of permatrip, synonym of burnt out

a: "You notice Jake lately? He seems a little slower than usual"
b: "Smokes way too much, man. He's in a perpetual state of permaderp."

Permaderp by Mingy Jongo February 5, 2010