Literally this means "in the fight". This is used by people in Latin America; in particular Puerto Rico, The Dominican Republic, and Cuba.
People use this to describe their daily struggles, in particular in regards to overcoming financial difficulties. When you are "en la lucha" life is difficult, and you are fighting to win.
¿Como estas? / How are you?
En la lucha, 'mano. / I'm in the fight, brother.
