1. When you are searching for something on google and you cannot find it, then you are perplexed.
2. When you are searching for something on Google and you type in one word and something completely unrelated pops up.
I was searching Google the other day for waffles and John Kerry's name come up, I was friggin google(tm)plexed
When you cannot think of anything else to say if you are in a hostile or scary situation.
Such as speeding in a car and you hit black ice, you can't control it, just go with it.