2 definitions by TheGentleman
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Condition experienced when an individual becomes slightly depressed and generally stagnant as a result of a recent departure from visiting friends in another geographical location.
"I had a great time this weekend, but after leaving behind the fun of the orgies, binge drinking, and non-stop hot-tubbing, I find myself in a state of Post-Departure Depression. FML"
by TheGentleman February 24, 2009