Z-tards are people who support the Russian invasion of Ukraine because they only read far-right news outlets and Russian news without acknowledging pro-Ukraine arguments. It comes from many pro-Russians using the letter Z (even though it's not in the Cyrillic alphabet) due to the Russian government pushing propaganda making Z look like their symbol of allegiance.
John: Did you see David larping about how Ukraine deserved it yesterday?
Emily: Yeah, he looks like a Z-tard.
Emily: Yeah, he looks like a Z-tard.
by PrivateerFlujt May 29, 2022