To screw over on an epic level. To be taken advantage of so bad that you feel like you took it in the behind or up the butthole.
Wow, I can't believe I was robbed by those so called friends of mine, I am going to wronghole them as soon as I get a chance!
To throw up without notice or warning signs. Spontaneous barfing, no sickness involved.
Why did I bafe everywhere while in front of everyone!