1 definition by FMSL
The sickness that one experiences after ingesting the 5.99 CiCi's Pizza buffet where one cannot even make it out of the building before shitting on ones self.
Wayne: "Hey man lets go to CiCi's I have a Groupon!"
Corey: "Nah Son, fuck that! Last time CiCi's Syndrome hit me so hard with explosive diarrhea I thought I had macaroni pizza running down my leg!"
Corey: "Nah Son, fuck that! Last time CiCi's Syndrome hit me so hard with explosive diarrhea I thought I had macaroni pizza running down my leg!"
by FMSL August 6, 2011