1. a. In a state somewhat equivalent to a bad high; when the mind interprets things in the physical realm differently from what they really are (commonly location based)
b. Somewhat similar to trip, but in a more negative way
2. When the mind freaks out similarly to an excited panic attack
3. To be in a state of high excitement
2. "Whoa, I thought that cat jumped at me, I saw it outta the corner of my eye!"
"Naw man, you're just tweaking out."
3. "Oh shit man, what are we gonna do? I just shot a cop! What are we gonna do? I'm tweaking out man, I'm tweaking out!!"