Top definition
A person doing lots of meth in a short period of time. Also known as a tweaker.
Guy 1: man Johns really tweaked out.
Guy 2: yeah I know. Hes a tweaker.
by PinkPanada April 26, 2016
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2
A person typically and habitually under the influence of cocaine, methamphetamine, diacetylmorphine, and any other tweaker choice you could think of.
Bob: Hey Jimmy see that guy over there?
Jimmy: Yeah man, he's acting pretty weird.

Bob: Eh, must be tweaked out or something .
Jimmy: On the real lets keep movin.
by Burberry Hilfiger January 16, 2016
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