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1) n. In New England, it is a brass musical instument, conical in construction, about 18 feet long, with a large mouthpiece, and is the lowest of the brass instruments. It replaced the ophiclede in the symphony orchestra, and has nothing to do with Wagner Tubas. It has only one direct cousin in brass instruments, that being the fluglehorn, for all other brass instruments are more cylindrical than the tuber, even the french horn.
2) n. For the rest of the English-speaking world, it is a fleshy-rooted plant like a potato or a yam. Hence, New Englanders and Non-New Englanders can get confused at times, as evidenced below.
An actual conversation:
Denny: Dan, can you play the tuber for the Bristol, RI band next weekend?
Dan: Well Denny, do you want me to play 1st or 2nd potato?
tuber by Dan1271 November 13, 2007
Related Words

Tuberculosis

A disease that killed the most Bad ass character in Red Dead Redemption 2
Arthur: We are not a charity

Man: Spits on Arthur

That’s how he got tuberculosis

Tik-Tuber 

A person from or on TikTok that post's their cringe on YouTube
1: Hey did you see that new Tik-Tuber

2: How the hell would I know you didn’t specify the person there’s like a thousand

1: Oh well nevermind
Tik-Tuber by ThatDeadsoulGuyyt July 21, 2021

pull a tube 

To take a hit from the bong.
Hey Steve let’s smoke a joint. Nah I’d rather pull a tube.
pull a tube by Louudog March 15, 2018

Tubesteak Shuffle 

Sexual Intercourse; To throw your salami into a hopefully acceptable orifice.
Friend 1: Hey look at that hot chick over at the bar.

Friend 2: That's easy money man. I gave her the tubesteak shuffle last week.

Tuber simulator 

A still relevant game for mobiles and the game is available for free and that’s a great price
WHHHHAAATTTT!!! You’ve never played tuber simulator??
-PewDiePie