Singular Sclerosis 

The retarded cousin of Multiple Sclerosis, this disease only affects male genitals, causing complete numbness, leading to permanent, untreatable erectile dysfunction.

Doctor: You've been diagnosed with Singular Sclerosis. You will never be able to pound Zucker's fat, hairy ass again.

Stelter: God dammit Donald Trump!

Singular Sclerosis by sciflyer.25 April 22, 2020

Scroticure

A long, lavish treatment of the seminal sack: including manscape, massage and manipulation.  Often involves scented candles and rooting for The Redskins.

After losing the Fantasy Football Championship, Karl was compelled to perform a poignant and personal scroticure.

Scroticure by KlawzVengeance January 24, 2012

Scroticular 

of or pertaining to the scrotum

When Bill sat on his nuts, he pinched a scroticular nerve

Scroticular by Ryan O'Beirne July 25, 2003

Scroticles 

(noun) The scrotal/testicular region.

\"Pinky was a nice cat, until he bit me in the scroticles.\"

Scroticles by LittleSam April 26, 2005

multiple scleropissed 

An extreme state of drunkenness to such an extent that results in fatigue, difficulty with walking, vision, balance, thinking, speech and co-ordination and loss of control of muscles and bladder control.

I wish I hadn't had that final shot, I went from being drunk to full on multiple scleropissed and had to be carried home. Oh and I wet the bed three times.

multiple scleropissed by Fatladdc August 27, 2016

Sclerotia 

A hardened mycelium mass that contains both psilocybin and psilicon. Commonly refereed to as "philosopher stones," they produce a trip very similar if not identical to that of the p. cubensis "shroom" species.
Sclerotia is produced invitro, making it much more stealthy and easy to grow as compared to the actual mushrooms the sclerotia is capable of producing.
There are 3 strains currently available:

1.Psilocybe mexicana

2.Psilocybe tampanensis

3.Psilocybe atlantis

Dude! I just ate this sclerotia! I can't believe how amazing this is. I almost have pity on those that say all drugs are bad and are too closed minded to ever improve their lives.
Ha ha Mr. T pities the fool!

Oh my god! I am starting to realize there is so much more to life then buying this materialistic shit!
I need to stop polluting the air and being part of this wretched system. Oh how I love you sclerotia, you have shown me how to be a better and happier person!

Sclerotia by Inner Improvement Movement March 11, 2011

indigo sclerosis 

Indigo Sclerosis, or IS, is a short term disease that cant affect your brain, spinal cord, and the optic nerves in your eyes. It is a very rare variation of singular sclerosis. This condition is completely asymptomatic and it is particularly difficult to diagnose. Only by close inspection of the sclerosis will one find a sleight discoloration.

Sammy: Did you hear Matt was diagnosed with Indigo Sclerosis?

Mark: Yeah, he told me he was tired of explaining it to people over and over and that he wished there was more information about it available on the internet.

indigo sclerosis by Dixon_Ticonderoga January 5, 2017