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1.
OMFR, short for "Oh my fucking rod." The term "rod" is short for Rodney, from the internet video titled "Bubble Tea." This could also be interpretted as a paraody of OMFG, by replacing the g in God with an R.

Stems from the phrase OMG.
Sammy the Cashier: MUahahahahahaha! Muahahahah!

(OMFR sounds like he's dying! Call 991!)
by Mobus March 04, 2007