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1.
to attempt to master a difficult videogame/puzzle/craft to perfection in a matter of days by sitting on your ass for hours on end as if (or because) you have no life.
i just got gta 4 yesterday, i'm totally no-lifing that shit for 100%.
by silly hats only May 08, 2008
 
2.
To do months of work within days, reject social invitations, and only leave the house to buy take-away because you must work hard to do well. Synonymous with IT certifications or playing computer games.
Sorry dude, I cant come out tonight. I've gotta no-life Cisco, as I've only got 5 days left to complete the last 6 exams of my certification.

Yea man, the only way your going to finish that work is by No-Lifing it.
by {Perfect | Cypher} June 25, 2010
 
3.
To sit at home and play video/computer games all day.
Tomorrow I'm going to stay at home Nolifing WoW.
by MWH yo January 31, 2009