miss cain Share definition Flag miss cain is a stupid woman who doesn't know how to teach nor know the subject she is head of. Friend 1: Awh man! We have miss cain next. Friend 2: A little peace of me just died miss cain by Dobadom November 25, 2013 0 0 Get merch Get the miss cain mug. Buy Now — $32.95 See more merch