A person whose life has fallen into disrepair. Or one who is suffering the effects of intoxicating substances, perhaps on a prolonged basis.
Grant woke up at 3 in the afternoon after drinking all night, smacking his bird, pissing over his living room carpet and listening to back to back babyshambles LPs. He then cracked open anothe special brew and switched MTV on. 'MESS!'
by Dan Daman December 30, 2005
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1. it meens to bug or get on someones bad side

2. i've also heard it as a good term sayin i mess wit someone meening i roll wit that person
Example:

1. Yo boii don mess with me or i'll knock u out

2. YEA! did u see Jose man he popped 6 thugs! yea das y i mess with him
by Terencio July 12, 2006
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Usally refers to male who has recently shit themself. However, not referring to a woman, that would be a "brown leaf"
by 2d00dgetinf00d May 9, 2017
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Synonym for sperm/semen, preferably when ejaculated onto a surface.
Man, I laid the mess on Donna's face last night!

by Frank Johnson Esq. December 14, 2007
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A person, generally female, who refers to her/himself as a Hot Mess, but in reality is not a Hot Mess because they are either not currently a mess or, more likely, they are simply not hot. Typically, the subject is under the mistaken impression they are hot.
(overweight) Girl: I'm super-busy, I've lost my keys, my phone is dead, and I've got a million things to do - I'm a hot mess!

You (to friend, whispering): She's not hot...so really she's a Not Mess.
by Phil-ys March 26, 2013
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not looking rite; doing something or saying something thats not rite;stupid;needs to stop
you look a mess
by lil treezy March 12, 2003
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